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Home > Help Desk > Health Concern > Health Concern C > Celiac Disease

Celiac Disease

Celiac disease (also called gluten enteropathy) is an intestinal disorder that results from an abnormal immunological reaction to gluten, a protein found in wheat, barley, rye, and to a lesser extent, oats. In addition to damaging the lining of the small intestine, celiac disease can sometimes affect other parts of the body, such as the pancreas (increasing the risk of diabetes), the thyroid gland (increasing the risk of thyroid disease), and the nervous system (increasing the risk of peripheral neuropathies and other neurological disorders). Occasionally, such damage occurs only in one or more of these parts of the body in the absence of damage to the intestines.

What are the symptoms of celiac disease?
Celiac disease may not cause symptoms in some people. However, others may have a history of frequent diarrhea; pale, foul-smelling, bulky stools; abdominal pain, gas, and bloating; weight loss; fatigue; canker sores; muscle cramps; delayed growth or short stature; bone and joint pain; seizures; painful skin rash; or infertility. Microscopic examination of the small-intestinal lining reveals severe damage, especially in the jejunum (the central portion of the small intestines). People with untreated celiac disease may eventually experience malaise and weight loss and have an increased risk of developing anemia, osteoporosis, osteomalacia, and certain types of cancer. In addition to physical symptoms, some people may experience emotional disturbances, including feelings of anxiety and depression.

How is it treated?
The conventional treatment is strict adherence to a gluten-free diet although doctors are increasingly questioning the need for all celiac patients to avoid oats. People with severe damage to the absorptive surface of their intestines may also be prescribed intravenous nutritional supplements. Immunosuppressive and anti-inflammatory medications, such as glucocorticoids are sometimes used as components of conventional treatment.

Dietary changes that may be helpful:
All doctors agree that consumption of the gluten-containing grains wheat, barley, and rye must be avoided in all celiac patients. Less consensus exists regarding the advisability of eating or restricting oats and oat products. While oats contain a substance similar to gluten, modern research suggests that eating moderate amounts of oats does not cause problems for most people with celiac disease.

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