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Home > Conditions A-Z > Gout Arthritis
Home > Help Desk > Health Concern > Section G > Gout Arthritis

Gout Arthritis

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Gout is a form of arthritis that occurs when crystals of uric acid accumulate in a joint, leading to the sudden development of pain and inflammation. People with gout either overproduce uric acid or are less efficient than other people, at eliminating it. The joint of the big toe is the most common site to accumulate uric acid crystals, although other joints may be affected.

What are the symptoms of gout?
The pain of gout can arise suddenly and is often very intense. The affected joint is usually red, swollen, and very tender to the touch. A low-grade fever may also be present.

How is it treated?
Acute gout attacks are typically treated with colchicine, nonsteroidal anti-inflammatory drugs such as indomethacin or naproxen sodium, and corticosteroids. Resting the affected joint is commonly recommended. For long-term treatment, doctors may prescribe medications such as allopurinol (Lopurim®, Zyloprim®) to decrease uric acid production, or probenecid (Benemid®) or sulfinpyrazone (Anturane®) to increase the excretion of uric acid from the kidneys.

Dietary changes that may be helpful:
Foods that are high in compounds called purines raise uric acid levels in the body and increase the risk of gout. Restricting purine intake can reduce the risk of an attack in people susceptible to gout. Foods high in purines include anchovies, bouillon, brains, broth, consommé, dried legumes, goose, gravy, heart, herring, kidneys, liver, mackerel, meat extracts, mincemeat, mussels, partridge, fish roe, sardines, scallops, shrimp, sweetbreads, baker’s yeast, brewer’s yeast, and yeast extracts.

Lifestyle changes that may be helpful:
People who are overweight or have high blood pressure are at greater risk of developing gout. However, weight loss should not be rapid because restriction of calories can increase uric acid levels temporarily, which may aggravate the condition.

Nutritional supplements that may be helpful:
Large amounts of supplemental folic acid (up to 80 mg per day) have reduced uric acid levels in preliminary research. However, other studies have failed to confirm the effectiveness of folic acid in treating people with gout.

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