Grape Seed Extract


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Flora, Grape Seed Extract Plus, 60 Vegetarian CapsulesCost Per Serving : $0.62 |
Grape Seed Extract, 100 Capsules, 100mg, GSE-100Cost Per Serving : $0.20 |
MegaNatural, BP Grape Seed Extract, 60 Capsules, 150 mg, From Healthy OriginsCost Per Serving : $0.19 |
MegaNatural-BP Grape Seed Extract, 60 Capsules, 300 mg, From Healthy OriginsCost Per Serving : $0.33 |
Jarrow Formulas, OPCs + 95, Grape Seed Extract, 100 mg, 100 CapsulesCost Per Serving : $0.23 |
Now Foods, Grape Seed, Standardized Extract, 100 mg, 200 Veg CapsulesCost Per Serving : $0.14 |
Grape Seed Extract, 120 Tablets, 100 mg, From Source NaturalsCost Per Serving : $0.15 |
Natural Factors, Horse Chestnut with GrapeSeedRich, 350 mg, 60 CapsulesCost Per Serving : $0.25 |
Natural Factors, GrapeSeedRich, Grape Seed Extract, 100 mg, 90 Vegetarian CapsulesCost Per Serving : $0.21 |
Jarrow Formulas, Vision Optimizer, 90 Veggie CapsCost Per Serving : $0.32 |
Jarrow Formulas Women's Multi with Iron, Multi-Vitamin Mineral Formula, 60 Tablets, From JarrowCost Per Serving : $0.13 |
Now Foods, Cranberry with PACs, 90 Veg CapsulesCost Per Serving : $0.15 |


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Grape Seed Extract
Grape Seed Extract
Oligomeric proanthocyanidins, better known by the abbreviation OPCs, are classified as flavonols and are usually derived from grape seeds or pine bark. They are also present in red wine, hops, and various flowers, leaves, fruits, berries, nuts, and beans, usually with high concentrations in skins, barks, and seeds. The way in which these versatile healing compounds are distinct from flavonoids is their simple chemical structure, which allows them to be readily absorbed into the bloodstream.
OPCs are very powerful antioxidants. Vitamin E defends against fat-soluble oxidants, and vitamin C neutralizes water-soluble ones, but OPCs are active against both types. They also help stabilize the walls of blood vessels, reduce inflammation, and generally support tissues containing collagen and elastin, proteins found in cartilage, tendons, blood vessels, skin, and muscle.
Of all the herbs and herbal supplements, OPCs are the most useful in supporting vascular health. They maintain the health of capillaries, which are the channels through which the blood delivers nutrients to individual cells and carries away waste products. Capillaries must be permeable enough to allow nutrients and oxygen to seep through them, but strong enough to prevent too much fluid from flowing out and causing edema. The beneficial effects of OPCs on capillary health result in relief of many neurological diseases and can prevent the swelling and inflammation of allergic reactions. OPCs are popular for preventing heart disease, revitalizing aging skin, and reducing a tendency to bruise easily.
OPC Grape Seed Extract which is high in Oligomeric Proanthocyanidins is powerful antioxidant which can reduce the damage done by free radicals, strengthen and repair connective tissue, and promote enzyme activity. OPC Grape Seed Extract can also help moderate allergic and inflammatory responses by reducing histamine production. As an antioxidant, OPC Grape Seed Extract are 20 times more powerful than vitamin C and 50 times more powerful than vitamin E. OPC (Grape Seed Extract) are important to your health for many reasons, including:
Enhance Your Circulatory System
Research has shown that OPC (Grape Seed Extract) play an important role in maintaining the health of capillaries and veins. For this reason, OPC (Grape Seed Extract) have successfully used to help improve bulging veins in the legs, poor circulation and to enhance visual function. Clinical studies have shown that OPC (Grape Seed Extract) can benefit the body by supporting healthy blood flow through the arteries and veins.
Benefits of OPC (Grape Seed Extract) for specific health conditions include the following:
OPC (Grape Seed Extract) are also known to be potent antioxidants. If blood circulation to the brain of a person with ADD is impeded by allergy, high blood pressure, or muscular tension, the brain's oxygen supply is reduced. Once circulation is restored, toxic free radicals released by oxidation can flood brain tissue, destroying the linings of cells. OPCs interrupt the formation of oxygen free radicals and prevent damage to cell membranes. According to recent research, OPCs also help deliver to the brain nutrients that are helpful for people with ADD, such as zinc, manganese, selenium, and copper. OPCs also relieve neurological symptoms by acting as antihistamines. Allergic reactions can cause pain signals in the rest of the body that can overwhelm the brain, interfering with its functions of coordination and control and heightening the symptoms of ADD. By fighting allergies elsewhere, OPCs can reduce the burden on the brain and relieve symptoms of ADD.
The body's overproduction of nitrous oxide (NO) can result in chronic, damaging inflammation, which is the root cause of one in three cancers. Pycnogenol has been shown to quench NO when it threatens to become a damaging free radical, and it inhibits a gene that might otherwise create enzymes that could lead to the overproduction of NO. Diabetic retinopathy and macular degeneration. Professor Denham Harman of the University of Nebraska believes that OPCs may be the ideal for macular degeneration. Proanthocyanidins concentrate in the linings of microscopic blood vessels in the eye. These delicate conduits for blood are easily blocked by cellular debris or inflammation. They are also sensitive to injury from high blood pressure or diabetes. As long as the right level of permeability is maintained, however, no damage occurs to the retina. OPCs keep the capillaries permeable enough to deliver nutrients and remove waste products. They prevent excessive permeability that would cause swelling in the nerve tissue itself.
Harman believes that the antioxidant action of proanthocyanidins also helps to protect eye tissue from damage caused by inconsistent levels of oxygen. Two unpublished studies of 100 subjects found that taking 200 milligrams of grape seed OPCs for five weeks produced improvements in night vision and glare recovery. In other studies, OPCs have been shown to relieve eyestrain in computer users, to reduce retinopathy among people with diabetes, and to improve the function of the retina in nearsighted people. High blood pressure and stroke. People with high blood pressure have weakened capillaries that allow fluid to pass through the walls and into the tissues very easily. The tendency of capillaries to break increases the risk of hemorrhagic stroke and ruptured blood vessels. French researchers have found that grape seed OPCs increase capillary resistance by 25 percent in people with diabetes and/or high blood pressure. German studies have found that damage from stroke is much lower in laboratory animals first treated with OPCs.
Swollen ankles, cuts and scrapes, lymphedema, nosebleed, tendinitis, and varicose veins. When the walls of small blood vessels weaken, the fluids they transport leak out, causing swelling. OPCs strengthen capillary walls by blocking the degradation of the two proteins that give them strength and elasticity, collagen and elastin. This action stops edema and swelling.
The ability of OPCs to strengthen capillary walls has been scientifically verified. A double-blind Italian study of fifty people with varicose veins found that grape seed OPCs worked faster and longer than the most commonly used prescription medication. The OPCs relieved both the burning and tingling sensations caused by varicose veins and swelling in the lower extremities. All symptoms improved in just thirty days. A French study found that 300 milligrams of grape seed OPCs taken daily for four weeks reduced the reported incidence of pain, nighttime leg cramps, swelling, and tingling by 50 percent. Although OPCs can relieve the pain and swelling of venous insufficiency, they cannot make visible varicose veins disappear. But regular use might help prevent new ones from developing.
There is some evidence that OPCs can be useful for swelling following an injury or surgery. A double-blind controlled study found that postoperative breast cancer patients who took 600 milligrams of OPCs daily for six months experienced a significant reduction in swelling, pain, and sensations known as paresthesias. Another double-blind controlled study found that OPCs improved the rate at which swelling disappeared following sports injuries.
The two principal sources of OPCs are a pine-bark extract called Pycnogenol and a number of products based on grape seed extract. Both kinds of products supply the active ingredients that are important to vascular health and circulation. Products made from cranberries, hazelnut tree leaves, and lemon tree bark that have been standardized for proanthocyanidins may also be used.
Many nutritionally oriented physicians report best results when Pycnogenol is taken in a dosage of 1 milligram per day for each pound of body weight (or 2 milligrams for each kilogram). For a 150-pound (70-kilogram) person, this would be a dose of approximately 150 milligrams of Pycnogenol daily. If progress is not satisfactory after thirty days, you can double the dosage. However, if you experience any signs of detoxification, such as congestion, fever, rash, diarrhea, headaches, irritability, or fatigue, you should increase the dosage more slowly.
Grape seed extracts are high in tannin and may interfere with iron absorption. You should not take these if you have anemia. If you are taking blood-thinning medication, including aspirin, heparin, pentoxifylline (Trental), or warfarin (Coumadin), high doses of OPCs may pose a risk of excessive bleeding.



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